VitaSynol® C is a highly stable, oil-soluble Vitamin C ester engineered to deliver targeted skin benefits through the gradual release of active Vitamin C. While it lacks inherent antioxidant activity due to complete esterification of its hydroxyl groups, VitaSynol® C acts as a true precursor—releasing Vitamin C within the skin to combat UVB-induced cell damage and reduce ROS-driven melanogenesis.

Key Features

• True Vitamin C precursor: Delivers active benefits through enzymatic release

• Superior stability: Resists heat and oxidation far better than traditional Vitamin C

• Enhanced absorption: Lipophilic nature improves skin penetration

• Formulation flexibility: Easily incorporated into oil-based systems

• Formulation tip: Since the release of Vitamin C may take hours before it shows a protective effect, it’s important to include an effective antioxidant like Synoxyl® AZ or Sytenol® A to VitaSynol® C formulations

Synoxyl® AZ is a high-purity (≥99%) multi-targeted anti-aging active developed to both prevent premature skin aging and visibly reverse signs of photo-damage. Designed to work proactively, Synoxyl® AZ helps protect the skin from environmental stressors while supporting its natural ability to preserve and repair the extracellular matrix (ECM)—a critical component for maintaining firmness, elasticity, and overall skin health.

In addition to its anti-aging efficacy, Synoxyl® AZ promotes microbiome balance by enhancing microbial diversity and stimulating the growth of beneficial skin flora such as Staphylococcus epidermidis by over 20%, contributing to a more resilient, healthier-looking complexion.

Synovea® EL is Ethyl Linoleate, a lipid-soluble and oxidation-resistant form of Linoleic Acid (LA)—an essential fatty acid vital for skin health and nourishment. Unlike free LA, Synovea® EL offers enhanced formulation stability, making it ideal for high-performance skincare products. In vivo studies have shown that EL is enzymatically hydrolyzed to release active LA (Alcohol Clin Exp Res, 1995), delivering all the known skin benefits of linoleic acid with the added advantage of improved shelf-life and formulation flexibility.

In addition to its role in barrier repair and anti-inflammatory care, Synovea® EL also functions as an effective solubilizer for hydrophobic active ingredients, including Avobenzone and Hexylresorcinol (Synovea® HR), further expanding its value in sunscreen, skin brightening, and anti-aging formulations.

Synovea® HR is a high-purity form of 4-Hexylresorcinol (HR) — a naturally occurring alkylresorcinol derived from cereal grains like rye. With over 80 years of safe use in the food and pharmaceutical industries, HR holds GRAS status and is widely recognized for its effectiveness as an anti-browning agent in shrimp and fresh-cut produce.

Now redefined for advanced skincare,  Synovea® HR was created as a powerful skin lightening and tone-evening ingredient. Its effectiveness is linked to its exceptional purity (≥99.5–99.9%), eliminating trace levels of resorcinol — a known skin irritant — and hexanoylresorcinol intermediates.

Proven Efficacy, Backed by Clinical Science

• A randomized, double-blind study conducted by UC-Davis dermatologists showed 1% Synovea® HR performs equivalently to 2% hydroquinone in reducing visible pigmentation on the face and hands — with excellent tolerance (Wu et al., Archives of Dermatological Research, 2022).

• A Unilever-sponsored study found synergistic effects between HR and niacinamide, enhancing anti-melanogenic activity in vitro, and confirming in vivo safety and efficacy in human trials (R. Shariff et al., Int. J. Cosmetic Science, 2021).

Key Benefits:

• Brightens and evens skin tone with high efficacy

• High purity minimizes irritation and maximizes performance

• Demonstrated synergy with niacinamide

• Clinically proven results on both face and hands

• Well tolerated and safe for topical use, even on sensitive skin

Synactin® AC is a synergistic blend of Hexylresorcinol (HR) and Ethyl Linoleate (EL) in a skin-friendly carrier (caprylic/capric triglycerides). It targets all five major causes of acne, including regulation of keratinization, controlling sebum production, reducing bacterial overgrowth, calming inflammation, and minimizing post-inflammatory hyperpigmentation.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.

Hydra Synol® DOI is a well-defined compound, lipophilic with excellent skin feel and is completely odorless. It is a smart skin hydrator and barrier builder that intelligently provides optimum hydration based on skin
moisture content/deficit.

Key Features:

• Clinically shown to be very effective in providing long-lasting (>48 hrs.) and controlled skin hydration.
• The beneficial effects on the skin can be explained by the up-regulation of AQP3, CD44 (hyaluronic acid receptor) and tight junction genes, decrease of which is associated with a defective osmotic equilibrium in the epidermis and dryness of chronically and photoaged skin.
• It stimulates ceramide synthase 3, key enzyme responsible for Ceramide boosting.
• DOI has unique anti-inflammatory properties, works by inhibiting TRPA1, TSLP, TRPV3, IL1β and TNFα pathways.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.

By adding Synovea® HR (Hexylresorcinol) and Synovea® EL (Ethyl Linoleate) to the skin-friendly emollient Caprylic/Capric Triglycerides Sytheon has created an elegant, easy-to-use and very cost-effective new synergistic skin lightening blend – Asyntra® SL. Ethyl Linoleate is a very good solubilizer for HR and is a stable form of Linoleic acid. Linoleic acid is an essential fatty acid, a precursor of ceramides and a major component of skin lipids. EL is clinically proven to lighten UV-induced skin pigmentation by accelerating post-translational proteolytic degradation of tyrosinase.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.

Sytenol® A is the first natural alternative to retinol, offering comparable clinical performance without the irritation, dryness, or sensitivity often associated with traditional retinoids.

With a purity of ≥99%, it is both photochemically and hydrolytically stable, allowing for safe daytime use without photosensitivity concerns. Extensive studies show that Sytenol® A modulates retinoid-binding and metabolizing genes, significantly improves dermal and dermo-epidermal junction proteins, and stimulates Collagen I, III, and IV production for stronger, firmer skin. It also enhances hydration by upregulating hyaluronic acid and aquaporin 3 synthesis.

Highlights:

• As a plant-based compound, it offers a gentler alternative to synthetic retinol, with a lower risk of irritation.
• In a 12-week study, bakuchiol users reported up to 5 times less facial skin scaling and stinging than retinol users.
• The same study showed a 59% reduction in hyperpigmentation, compared to only a 44% reduction in the retinol group.
• Unlike some retinoids, it is photostable, i.e., it’s stable when exposed to light, making it suitable for daytime use.

In the years since the team at Sytheon, now part of Hallstar, introduced Sytenol® A Bakuchiol to the world, they have conducted rigorous research and published extensive data on its multiple benefit,s ensuring scientific precision, reliability, and proven safety.

Clinically, Sytenol® A delivers visible reduction in skin roughness, dryness, fine lines, and wrinkles, while improving tone, elasticity, firmness, radiance, and brightness — redefining what’s possible with natural skincare. Suggested use levels are 0.5 to 1%.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.